Liver Self-Repair

Prof. Satdarshan Singh Monga discusses his team’s investigation into liver regeneration as an alternative to waiting for a transplant

The liver is known for its ability to regenerate (see last issue’s cover story for more information). It can completely regrow itself even after two-thirds of its mass has been surgically removed. But damage from medications, alcohol abuse or obesity can eventually cause the liver to fail. Currently, the only effective treatment for end-stage liver disease is transplantation.

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Are Livers Forever Young?

Of all the body’s organs, the liver has the greatest power to regenerate itself.

Liver cell replacement and regeneration are vital functions that keep us feeling well and also maintain healthy metabolic activity. Some have suggested this is even the origin of the myth of Prometheus, whose liver was pecked out by an eagle each day, only to regrow each night.

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